Abstract: In order to discuss opening and cavity shear flow-induced vibration and structural coupling resonance, experiments of opening and cavity shear flow-induced vibration and structural noise control are carried out. The impact of the opening size, flow velocity and cavity thickness on shear oscillation noise, self-noise in the cavity and radiated noise are analyzed. The results show that the empirical formula of the opening shear oscillation in air is also applicable to the condition underwater, which the shear oscillation and amplitude of modal frequencies are directly proportional to the flow velocity; in case that no coupling resonance occurs, the thickness of the cavity wall will bring slight influence on the amplitude of the shear oscillation, but not on the mode frequencies; also the coupling of shear oscillatory mode and cavity wall mode show dramatic coupling resonance under certain conditions, and leads to self-noise and acoustic radiation. The findings supply useful exploration and technical support concerning the application of opening and cavity structural noise control measures.