Abstract: As the turbulent boundary layer (TBL) is one of the most important sources of vibration and noise in underwater vehicles, there is an important significance in studying the numerical method for the calculation of flow-induced noise. In this paper, the methods of Principal Component Analysis (PCA) and Vibro-Acoustic Transfer Vectors (VATV) based on LMS Virtual Lab software are used to calculate the sound characteristics of a plate structure excited by TBL. The Corcos model of the wave number-frequency spectrum of the wall pressure field beneath the TBL is used to describe random excitation. By comparing the calculating time and sound pressure auto power spectra curves of the two methods, the following conclusions are obtained: both the VATV method and PCA method can be used effectively for the calculation of the flow-induced noise of structures excited by the TBL, and the results of the two methods match; the VATV method can quickly forecast the structure of flow-induced noise and takes up fewer computing resources than the PCA method; the PCA method can also obtain the structure vibration response in comparison with the VATV method. The current work can serve as a reference for the rapid prediction of the flow-induced noise of underwater structures.