Abstract: Based on the Geers and Hunter S Method of the bubble pulsation load in free field，the condition of free-field assumption was analyzed in this paper through the Kelvin Impulse Method.And the comparison of calculated results with the experimental data was carried out which indicated the validity of the algorithm.Analysis of different bubble responses of the simplified single-hull submarine structure shows that：when the distance between bubble and the structure is three times greater than bubble radius， the impact of structure to the bubble can be ignored；the response of structure subject to bubble pulsation can be solved effectively by the vibro-acoustic coupling method；under the low-frequency bubble pulsation load，the first-order and third-order vertical movement of the structure is aroused with the former as main style；when the first-order wet frequency of the structure differs from that of bubble pulsation with constant value，the trend of negative correlation is presented between the structure frequency and whip-like amplitude；when the frequency of bubble pulsation is close to the wet frequency of the structure，the peak of structure response appears.