Abstract: This study involves the design of a high speed vessel with a deep-Vee hull by using a nonlinear hull transformation to diversify the hull forms, then optimizing the hull forms by the potential flow CFD. Model tests which use the same dimension and displacement ship models show that the resistance performance of the optimized deep-Vee hull is equivalent to the round-bilge hull in its low Froudes number, with it keeps the advantage of resistance performance in high Froudes number. Moreover, the study provides seakeeping predictions for the optimized deep-Vee hull by strip theory, and compares the results of the theory predictions with the model test. The results of the model test show that strip theory is able to provide reasonably accurate seakeeping predictions for the thin deep-Vee hull.